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doi: 10.1038/nature05859 119 SimamuraEShimadaHHattaTHiraiKI
In this hypothesis, the homozygous thermolabile MTHFR mutation would predispose to folate deficiency, which is likely to increase the cardiovascular disease risk by elevating homocysteine levels
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However, CBX3 exhibited a minimal effect on 5-FU resistance
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